Mouse Ssh2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ssh2
Locus ID	237860
Kit Components	GA214752G1, Ssh2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214752G2, Ssh2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214752G3, Ssh2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001291190, NM_177710
Synonyms	mSSH-2L; SSH-2; SSH-2L
Summary	Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.[UniProtKB/Swiss-Prot Function]

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