Mouse Zc3h12d activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Zc3h12d
Locus ID	237256
Kit Components	GA214713G1, Zc3h12d gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214713G2, Zc3h12d gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214713G3, Zc3h12d gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_172785
Synonyms	D730019B10Rik; TFL
Summary	May regulate cell growth likely by suppressing RB1 phosphorylation (By similarity). May function as RNase and regulate the levels of target RNA species (Potential). In association with ZC3H12A enhances the degradation of interleukin IL-6 mRNA level in activated macrophages (PubMed:26134560). Serve as a tumor suppressor in certain leukemia cells (By similarity). Overexpression inhibits the G1 to S phase progression through suppression of RB1 phosphorylation (By similarity).[UniProtKB/Swiss-Prot Function]

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