Mouse Vac14 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Vac14
Locus ID	234729
Kit Components	GA214563G1, Vac14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214563G2, Vac14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214563G3, Vac14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_146216, NR_151674, NR_151675
Synonyms	AA959718; BC032215; D8Wsu151e; ingls; Tax1bp2; Trx
Summary	The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts as a positive activator of PIKfyve kinase activity. Also required to maintain normal levels of phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P). Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.[UniProtKB/Swiss-Prot Function]

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