Mouse Tat activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tat
Locus ID	234724
Kit Components	GA214560G1, Tat gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214560G2, Tat gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214560G3, Tat gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_146214
Synonyms	MGC37772; MGC37789; MGC37790; MGC37819; MGC37828; MGC37842
Summary	This gene encodes a liver-specific mitochondrial enzyme that catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Regulated by glucocorticoid and polypeptide hormones, this gene's expression is affected by deletion of a regulatory region near the albino locus on chromosome 7. Mutations in this gene cause tyrosinemia type II in humans. [provided by RefSeq, Mar 2010]

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