Mouse Inpp4b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Inpp4b
Locus ID	234515
Kit Components	GA214539G1, Inpp4b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214539G2, Inpp4b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214539G3, Inpp4b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001024617, NM_001297591, NM_001297593, NM_001297596
Synonyms	E130107I17Rik
Summary	Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 3,4-bisphosphate (By similarity). Plays a role in the late stages of macropinocytosis by dephosphorylating phosphatidylinositol 3,4-bisphosphate in membrane ruffles (By similarity). Antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival (By similarity).[UniProtKB/Swiss-Prot Function]

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