Mouse Tti2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tti2
Locus ID	234138
Kit Components	GA214511G1, Tti2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214511G2, Tti2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214511G3, Tti2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001112729, NM_001199988, NM_144927, NR_103719
Synonyms	MGC28346
Summary	Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs (By similarity).[UniProtKB/Swiss-Prot Function]

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