Mouse Mosmo activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mosmo
Locus ID	233812
Kit Components	GA214479G1, Mosmo gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214479G2, Mosmo gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214479G3, Mosmo gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001164580
Synonyms	MGC40669
Summary	Acts as a negative regulator of hedgehog signaling probably by promoting internalization and subsequent degradation of smoothened protein (SMO) present in the ciliary membrane (PubMed:29290584). Plays a role in sonic hedgehog (SHH)-induced spinal neural progenitor cells differentiation (PubMed:29290584).[UniProtKB/Swiss-Prot Function]

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