Mouse Synm activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Synm
Locus ID	233335
Kit Components	GA214452G1, Synm gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214452G2, Synm gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214452G3, Synm gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_183312, NM_201639, NM_207663
Synonyms	4930412K21Rik; AI852401; Dmn; E130104F11; Syn; Synemin
Summary	Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells (By similarity).[UniProtKB/Swiss-Prot Function]

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