Mouse Iqsec1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Iqsec1
Locus ID	232227
Kit Components	GA214339G1, Iqsec1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214339G2, Iqsec1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214339G3, Iqsec1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001134383, NM_001134384, NM_001356440, NM_182784
Synonyms	AW561907; BC026481; BRAG2; cI-43; D6Ertd349e
Summary	Guanine nucleotide exchange factor for ARF1 and ARF6. Guanine nucleotide exchange factor activity is enhanced by lipid binding. Accelerates GTP binding by ARFs of all three classes. Guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin.[UniProtKB/Swiss-Prot Function]

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