Mouse Alkbh2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Alkbh2
Locus ID	231642
Kit Components	GA214277G1, Alkbh2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214277G2, Alkbh2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214277G3, Alkbh2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_175016, NM_001359940, NM_001359941
Synonyms	9530023G02; Abh2; AU016977; mABH2
Summary	Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine. Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.[UniProtKB/Swiss-Prot Function]

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