Mouse Gckr activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gckr
Locus ID	231103
Kit Components	GA214239G1, Gckr gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214239G2, Gckr gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214239G3, Gckr gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_144909
Synonyms	GKRP
Summary	Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity (By similarity).[UniProtKB/Swiss-Prot Function]

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