Mouse Galnt11 activation kit by CRISPRa
CAT#: GA214233
Galnt11 CRISPRa kit - CRISPR gene activation of mouse polypeptide N-acetylgalactosaminyltransferase 11
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Galnt11 |
Locus ID | 231050 |
Kit Components | GA214233G1, Galnt11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214233G2, Galnt11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214233G3, Galnt11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_144908, NM_001359890 |
Synonyms | A430075I06Rik; AI648252; E430002F06Rik |
Summary | Polypeptide N-acetylgalactosaminyltransferase that catalyzes the initiation of protein O-linked glycosylation and is involved in left/right asymmetry by mediating O-glycosylation of NOTCH1. O-glycosylation of NOTCH1 promotes activation of NOTCH1, modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO). Polypeptide N-acetylgalactosaminyltransferases catalyze the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward MUC1, MUC4, and EA2 than GALNT1. Not involved in glycosylation of erythropoietin (EPO) (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN506276 | Galnt11 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |
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