Mouse Galnt11 activation kit by CRISPRa

CAT#: GA214233

Galnt11 CRISPRa kit - CRISPR gene activation of mouse polypeptide N-acetylgalactosaminyltransferase 11



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Galnt11
Locus ID 231050
Kit Components

GA214233G1, Galnt11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA214233G2, Galnt11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA214233G3, Galnt11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_144908, NM_001359890
Synonyms A430075I06Rik; AI648252; E430002F06Rik
Summary Polypeptide N-acetylgalactosaminyltransferase that catalyzes the initiation of protein O-linked glycosylation and is involved in left/right asymmetry by mediating O-glycosylation of NOTCH1. O-glycosylation of NOTCH1 promotes activation of NOTCH1, modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO). Polypeptide N-acetylgalactosaminyltransferases catalyze the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward MUC1, MUC4, and EA2 than GALNT1. Not involved in glycosylation of erythropoietin (EPO) (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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