Mouse Rap1gds1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rap1gds1
Locus ID	229877
Kit Components	GA214119G1, Rap1gds1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214119G2, Rap1gds1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214119G3, Rap1gds1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001040690, NM_001286759, NM_145544, NM_001356388
Synonyms	BC011279; GDS1
Summary	Stimulates GDP/GTP exchange reaction of a group of small GTP-binding proteins (G proteins) including Rap1a/Rap1b, RhoA, RhoB and KRas, by stimulating the dissociation of GDP from and the subsequent binding of GTP to each small G protein. Able to promote the Ca(2+) release from the endoplasmic reticulum via both inositol trisphosphate (Ins3P) and ryanodine sensitive receptors leading to a enhanced mitochondrial Ca(2+) uptake.[UniProtKB/Swiss-Prot Function]

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