Mouse Osbpl2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Osbpl2
Locus ID	228983
Kit Components	GA214052G1, Osbpl2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214052G2, Osbpl2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214052G3, Osbpl2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_144500
Synonyms	C130070J12Rik; mKIAA0772; ORP-2; Orp2
Summary	Intracellular transport protein that binds sterols and phospholipids and mediates lipid transport between intracellular compartments. Increases plasma membrane cholesterol levels and decreases phosphatidylinositol-4,5-bisphosphate levels in the cell membrane. Binds phosphoinositides, such as phosphatidylinositol-4,5-bisphosphate. Exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Binds cholesterol, dehydroergosterol, 22(R)-hydroxycholesterol and 25-hydroxycholesterol (in vitro).[UniProtKB/Swiss-Prot Function]

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