Mouse Ncoa5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ncoa5
Locus ID	228869
Kit Components	GA214043G1, Ncoa5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214043G2, Ncoa5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214043G3, Ncoa5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_144892
Synonyms	CIA
Summary	Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC in response to 17-beta-estradiol (E2) (By similarity).[UniProtKB/Swiss-Prot Function]

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