Mouse Phf20 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Phf20
Locus ID	228829
Kit Components	GA214036G1, Phf20 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214036G2, Phf20 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214036G3, Phf20 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_172674
Synonyms	6820402O20Rik
Summary	Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage (By similarity). Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 'Lys-16' acetylation (H4K16ac) levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues.[UniProtKB/Swiss-Prot Function]

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