Mouse Sestd1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sestd1
Locus ID	228071
Kit Components	GA213991G1, Sestd1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213991G2, Sestd1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213991G3, Sestd1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_175465
Synonyms	1500031J16Rik; A930010O20; Solo/Trio8
Summary	May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1 (By similarity).[UniProtKB/Swiss-Prot Function]

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