Mouse Mettl8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mettl8
Locus ID	228019
Kit Components	GA213987G1, Mettl8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213987G2, Mettl8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213987G3, Mettl8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001110512, NM_145524
Synonyms	BC004636; Tip
Summary	This locus encodes a member of the methyltransferase family, and is involved in chromatin remodeling. Transcripts from this locus can be induced or inhibited by cell stretch and affect cell differentiation in the myogenic or adipogenic pathways. Multiple transcript variants encoding different isoforms have been found for this gene. Additional splice variants have been described in the literature but they meet nonsense-mediated decay (NMD) criteria and are likely to be degraded as soon as they are transcribed. [provided by RefSeq, Jul 2008]

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