Mouse Gigyf2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gigyf2
Locus ID	227331
Kit Components	GA213921G1, Gigyf2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213921G2, Gigyf2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213921G3, Gigyf2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001110212, NM_146112
Synonyms	2610016F01Rik; A830080H02Rik; AI852361; AW259676; BC006835; mKIAA0642; Tnrc15
Summary	Key component of the 4EHP-GYF2 complex, a multiprotein complex that acts as a repressor of translation initiation (PubMed:26763119). In 4EHP-GYF2 the complex, acts as a factor that bridges EIF4E2 to ZFP36/TTP, linking translation repression with mRNA decay (PubMed:26763119). May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling, including IGF1 and insulin receptors (PubMed:12771153).[UniProtKB/Swiss-Prot Function]

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