Mouse Twnk activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Twnk
Locus ID	226153
Kit Components	GA213832G1, Twnk gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213832G2, Twnk gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213832G3, Twnk gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_153796, NM_001348254, NM_001348259
Synonyms	D19Ertd626e; PEO; Peo1; Twinl
Summary	Involved in mitochondrial DNA (mtDNA) metabolism. Could function as an adenine nucleotide-dependent DNA helicase. Function infered to be critical for lifetime maintenance of mtDNA integrity. May be a key regulator of mtDNA copy number in mammals.[UniProtKB/Swiss-Prot Function]

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