Mouse Cd226 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cd226
Locus ID	225825
Kit Components	GA213793G1, Cd226 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213793G2, Cd226 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213793G3, Cd226 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001039148, NM_001039149, NM_178687
Synonyms	BC051526; DNAM-1; DNAM1; Pta1; TLiSA1
Summary	Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding.[UniProtKB/Swiss-Prot Function]

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