Mouse Usp49 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Usp49
Locus ID	224836
Kit Components	GA213734G1, Usp49 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213734G2, Usp49 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213734G3, Usp49 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_198421
Synonyms	C330046L10Rik; Gm545
Summary	Specifically deubiquitinates histone H2B at 'Lys-120' (H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons (By similarity).[UniProtKB/Swiss-Prot Function]

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