Mouse Bnip1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Bnip1
Locus ID	224630
Kit Components	GA213704G1, Bnip1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213704G2, Bnip1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213704G3, Bnip1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_172149
Synonyms	2010005M06Rik; 5930429G21Rik; Sec20
Summary	As part of a SNARE complex may be involved in endoplasmic reticulum membranes fusion and be required for the maintenance of endoplasmic reticulum organization. Plays also a role in apoptosis. It is for instance required for endoplasmic reticulum stress-induced apoptosis. As a substrate of RNF185 interacting with SQSTM1, might also be involved in mitochondrial autophagy.[UniProtKB/Swiss-Prot Function]

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