Mouse Ccno activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ccno
Locus ID	218630
Kit Components	GA213559G1, Ccno gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213559G2, Ccno gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213559G3, Ccno gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001081062
Synonyms	C86987; Ccnu; E130318K11; Ung2
Summary	Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation. Acts downstream of MCIDAS to promote mother centriole amplification and maturation in preparation for apical docking (By similarity). May be involved in apoptosis in lymphoid cells; however, this result requires additional evidences in vivo. May be involved in oocyte meiotic resumption in oocytes.[UniProtKB/Swiss-Prot Function]

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