Mouse Cipc activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cipc
Locus ID	217732
Kit Components	GA213498G1, Cipc gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213498G2, Cipc gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213498G3, Cipc gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001289429, NM_001289430, NM_001289431, NM_001289432, NM_173735, NR_033623, NM_001364274
Synonyms	2310044G17Rik; AI842544; AI853744; Kiaa1737; mKIAA1737
Summary	Transcriptional repressor which may act as a negative-feedback regulator of CLOCK-ARNTL/BMAL1 transcriptional activity in the circadian-clock mechanism. May stimulate ARNTL/BMAL1-dependent phosphorylation of CLOCK (PubMed:17310242, PubMed:19414601). However, the physiogical relevance of these observations is unsure, since experiments in knockout mice showed that CIPC is not critially required for basic circadian clock (PubMed:25862660).[UniProtKB/Swiss-Prot Function]

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