Mouse Nek9 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nek9
Locus ID	217718
Kit Components	GA213496G1, Nek9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213496G2, Nek9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213496G3, Nek9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_145138
Synonyms	C130021H08Rik
Summary	Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues Important for G1/S transition and S phase progression. Phosphorylates NEK6 and NEK7 and stimulates their activity by releasing the autoinhibitory functions of Tyr-108 and Tyr-97 respectively (By similarity).[UniProtKB/Swiss-Prot Function]

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