Mouse Zfyve1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Zfyve1
Locus ID	217695
Kit Components	GA213490G1, Zfyve1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213490G2, Zfyve1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213490G3, Zfyve1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_183154, NM_001359166, NM_001359167, NM_001359168
Synonyms	DFCP1; G630053K23; mKIAA1589; TAFF1; ZNFN2A1
Summary	Plays a role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis (PubMed:30970241). Regulates the morphology, size and distribution of LDs (PubMed:31293035, PubMed:30970241). Mediates the formation of endoplasmic reticulum-lipid droplets (ER-LD) contact sites by forming a complex with RAB18 and ZW10 (By similarity). Binds to phosphatidylinositol 3-phosphate (PtdIns3P) through FYVE-type zinc finger (By similarity).[UniProtKB/Swiss-Prot Function]

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