Mouse Cdc27 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cdc27
Locus ID	217232
Kit Components	GA213446G1, Cdc27 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213446G2, Cdc27 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213446G3, Cdc27 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001285988, NM_001285989, NM_001285990, NM_145436
Synonyms	AI452358; APC3; BC023187
Summary	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).[UniProtKB/Swiss-Prot Function]

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