Mouse Tmem106a activation kit by CRISPRa
CAT#: GA213438
Tmem106a CRISPRa kit - CRISPR gene activation of mouse transmembrane protein 106A
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Tmem106a |
Locus ID | 217203 |
Kit Components | GA213438G1, Tmem106a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213438G2, Tmem106a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213438G3, Tmem106a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_144830, NM_001359325, NM_001359326, NM_001359327 |
Synonyms | 0610008L10Rik; AI043106; BC022145 |
Summary | Activates macrophages and polarizes them into M1-like macrophages through the activation of the MAPK and NF-kappaB signaling pathway (PubMed:26215746). Upon activation, upregulates the expression of CD80, CD86, CD69 and MHC II on macrophages, and induces the release of pro-inflammatory cytokines such as TNF, IL1B, IL6, CCL2 and nitric oxide (PubMed:26215746). May play a role in inhibition of proliferation and migration (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN517693 | Tmem106a - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |
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