Mouse Tmem106a activation kit by CRISPRa

CAT#: GA213438

Tmem106a CRISPRa kit - CRISPR gene activation of mouse transmembrane protein 106A



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Tmem106a
Locus ID 217203
Kit Components

GA213438G1, Tmem106a gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA213438G2, Tmem106a gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA213438G3, Tmem106a gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_144830, NM_001359325, NM_001359326, NM_001359327
Synonyms 0610008L10Rik; AI043106; BC022145
Summary Activates macrophages and polarizes them into M1-like macrophages through the activation of the MAPK and NF-kappaB signaling pathway (PubMed:26215746). Upon activation, upregulates the expression of CD80, CD86, CD69 and MHC II on macrophages, and induces the release of pro-inflammatory cytokines such as TNF, IL1B, IL6, CCL2 and nitric oxide (PubMed:26215746). May play a role in inhibition of proliferation and migration (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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