Mouse Arrdc1 activation kit by CRISPRa

CAT#: GA213296

Arrdc1 CRISPRa kit - CRISPR gene activation of mouse arrestin domain containing 1



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Arrdc1
Locus ID 215705
Kit Components

GA213296G1, Arrdc1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA213296G2, Arrdc1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA213296G3, Arrdc1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_001162485, NM_178408, NR_027876
Synonyms AI957342; BC004091
Summary Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (PubMed:23886940, PubMed:27462458). Through an ubiquitination-dependent mechanism plays for instance a role in the incorporation of SLC11A2 into extracellular vesicles (PubMed:27462458). More generally, plays a role in the extracellular transport of proteins between cells through the release in the extracellular space of microvesicles (By similarity). By participating to the ITCH-mediated ubiquitination and subsequent degradation of NOTCH1, negatively regulates the NOTCH signaling pathway (PubMed:23886940).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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