Mouse Pomgnt2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pomgnt2
Locus ID	215494
Kit Components	GA213287G1, Pomgnt2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213287G2, Pomgnt2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213287G3, Pomgnt2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001289558, NM_001289559, NM_001289560, NM_153540
Synonyms	Ago61; C85492; Gtdc2
Summary	O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein (By similarity). Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (PubMed:24256719).[UniProtKB/Swiss-Prot Function]

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