Mouse Astl activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Astl
Locus ID	215095
Kit Components	GA213260G1, Astl gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213260G2, Astl gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213260G3, Astl gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001291003, NM_172539
Synonyms	7420700F21; C87576; Sas1b
Summary	Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding.[UniProtKB/Swiss-Prot Function]

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