Mouse Arhgap29 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Arhgap29
Locus ID	214137
Kit Components	GA213195G1, Arhgap29 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213195G2, Arhgap29 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213195G3, Arhgap29 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_172525, NM_001356524
Synonyms	6720461J18Rik; A830014I19; AU040217; B130017I01Rik; C76601; Parg1
Summary	GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho (By similarity). In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis.[UniProtKB/Swiss-Prot Function]

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