Mouse Rbbp5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rbbp5
Locus ID	213464
Kit Components	GA213154G1, Rbbp5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213154G2, Rbbp5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213154G3, Rbbp5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_172517, NM_001357486, NM_001357487
Synonyms	4933411J24Rik; C330016J05
Summary	As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid. Does not affect ES cell self-renewal.[UniProtKB/Swiss-Prot Function]

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