Mouse Mylk3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mylk3
Locus ID	213435
Kit Components	GA213148G1, Mylk3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213148G2, Mylk3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213148G3, Mylk3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001297612, NM_175441
Synonyms	D830007F02Rik; MLCK
Summary	Kinase that phosphorylates MYL2 in vitro. Has been proposed to be calmodulin-dependent (PubMed:17885681), although MYL2 phosphorylation has also been observed in the presence or absence of calmodulin (PubMed:18202317). Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility.[UniProtKB/Swiss-Prot Function]

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