Mouse Dnd1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dnd1
Locus ID	213236
Kit Components	GA213136G1, Dnd1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213136G2, Dnd1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213136G3, Dnd1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_173383
Synonyms	BC034897; RBMS4; Ter
Summary	RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression (By similarity). Relieves miRNA repression in germline cells (By similarity). Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs (By similarity). Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3' UTR) of several mRNAs (By similarity). Does not bind to miRNAs (By similarity). Isoform 1 may play a role during primordial germ cell (PGC) survival. However, does not seem to be essential for PGC migration.[UniProtKB/Swiss-Prot Function]

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