Mouse Lpcat1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Lpcat1
Locus ID	210992
Kit Components	GA213003G1, Lpcat1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213003G2, Lpcat1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213003G3, Lpcat1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_145376, NM_001368681, NM_001368682
Synonyms	2900035H07Rik; Aytl2; BB137372; BC005662; C87117; LPCAT; rd11
Summary	Possesses both acyltransferase and acetyltransferase activities (PubMed:16704971). Activity is calcium-independent (PubMed:18285344). Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC) (PubMed:16704971, PubMed:18156367). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively (PubMed:16704971, PubMed:18285344). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology (PubMed:16704971). Involved in the regulation of lipid droplet number and size (By similarity).[UniProtKB/Swiss-Prot Function]

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