Mouse Yeats2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Yeats2
Locus ID	208146
Kit Components	GA212845G1, Yeats2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212845G2, Yeats2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212845G3, Yeats2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001033237, NM_001145930, NM_001145931
Synonyms	BC042768; mKIAA1197
Summary	Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors.[UniProtKB/Swiss-Prot Function]

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