Mouse Klf11 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Klf11
Locus ID	194655
Kit Components	GA212770G1, Klf11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212770G2, Klf11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212770G3, Klf11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_178357
Synonyms	9830142A17; D12Ertd427e; Tieg2; Tieg2b; Tieg3
Summary	Transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding sites inhibiting cell growth (By similarity). Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis.[UniProtKB/Swiss-Prot Function]

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