Mouse Nacad activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nacad
Locus ID	192950
Kit Components	GA212735G1, Nacad gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212735G2, Nacad gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212735G3, Nacad gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001081652
Synonyms	D230024G13Rik; mKIAA0363
Summary	May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity).[UniProtKB/Swiss-Prot Function]

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