Mouse Ripk2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ripk2
Locus ID	192656
Kit Components	GA212726G1, Ripk2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212726G2, Ripk2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212726G3, Ripk2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_138952, NR_138102
Synonyms	2210420D18Rik; CARD3; CARDIAK; CCK; D4Bwg0615e; RICK; RIP2
Summary	This gene encodes a member of the receptor-interacting protein family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain, and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of nuclear factor kappa B and inducer of apoptosis in response to various stimuli. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]

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