Mouse Phf21a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Phf21a
Locus ID	192285
Kit Components	GA212719G1, Phf21a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212719G2, Phf21a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212719G3, Phf21a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001109690, NM_001109691, NM_001346704, NM_138755, NM_001362829, NM_001362830, NM_001362831, NM_001362832, NM_001362833
Synonyms	80kDa; Bhc; Bhc80; D030065N23Rik; PFTF1
Summary	Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it may act as a scaffold. Inhibits KDM1A-mediated demethylation of 'Lys-4' of histone H3 in vitro, suggesting a role in demethylation regulation (By similarity).[UniProtKB/Swiss-Prot Function]

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