Mouse Elmo2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Elmo2
Locus ID	140579
Kit Components	GA212522G1, Elmo2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212522G2, Elmo2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212522G3, Elmo2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001302752, NM_001302754, NM_080287, NM_207705, NM_207706
Synonyms	1190002F24Rik; CED-12
Summary	Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity).[UniProtKB/Swiss-Prot Function]

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