Mouse Prdm15 activation kit by CRISPRa
CAT#: GA212422
Prdm15 CRISPRa kit - CRISPR gene activation of mouse PR domain containing 15
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Prdm15 |
Locus ID | 114604 |
Kit Components | GA212422G1, Prdm15 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212422G2, Prdm15 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212422G3, Prdm15 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_144789, NM_001359077, NM_001359078 |
Synonyms | C21orf83; E130018M06Rik; ORF62; Zfp298 |
Summary | Sequence-specific DNA-binding transcriptional regulator. Plays a role as a molecular node in a transcriptional network regulating embryonic development and cell fate decision. Stimulates the expression of upstream key transcriptional activators and repressors of the Wnt/beta-catenin and MAPK/ERK pathways, respectively, that are essential for naive pluripotency and self-renewal maintenance of embryonic stem cells (ESCs). Specifically promotes SPRY1 and RSPO1 transcription activation through recognition and direct binding of a specific DNA sequence in their promoter regions. Plays also a role in induced pluripotent stem cells (iPSCs) reprogramming. Involved in early embryo development.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN513832 | Prdm15 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |