Mouse Dok4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dok4
Locus ID	114255
Kit Components	GA212411G1, Dok4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212411G2, Dok4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212411G3, Dok4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_053246
Summary	DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells (By similarity).[UniProtKB/Swiss-Prot Function]

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