Mouse Scn4a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Scn4a
Locus ID	110880
Kit Components	GA212364G1, Scn4a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212364G2, Scn4a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212364G3, Scn4a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_133199
Synonyms	mH2; Nav1.4; SkM1
Summary	Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states (PubMed:11834499). Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles, and constant muscle strength in the presence of fluctuating K(+) levels (PubMed:18317596, PubMed:21881211).[UniProtKB/Swiss-Prot Function]

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