Mouse Dgkq activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dgkq
Locus ID	110524
Kit Components	GA212322G1, Dgkq gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212322G2, Dgkq gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212322G3, Dgkq gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_199011, NM_001357029
Synonyms	110kDa; DAGK; Dagk4; DAGK7; Dgkd
Summary	Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). May regulate the activity of protein kinase C by controlling the balance between these two signaling lipids. Activated in the nucleus in response to alpha-thrombin and nerve growth factor (By similarity). May be involved in cAMP-induced activation of NR5A1 and subsequent steroidogenic gene transcription by delivering PA as ligand for NR5A1. Acts synergistically with NR5A1 on CYP17 transcriptional activity (By similarity).[UniProtKB/Swiss-Prot Function]

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