Mouse Glo1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Glo1
Locus ID	109801
Kit Components	GA212255G1, Glo1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212255G2, Glo1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212255G3, Glo1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001113560, NM_025374
Synonyms	0610009E22Rik; 1110008E19Rik; 2510049H23Rik; AW550643; Glo-1; Glo-1r; Glo-1s; Glo1-r
Summary	Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B. Required for normal osteoclastogenesis.[UniProtKB/Swiss-Prot Function]

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