Mouse Mmaa activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mmaa
Locus ID	109136
Kit Components	GA212191G1, Mmaa gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212191G2, Mmaa gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212191G3, Mmaa gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_133823, NM_001363470, NM_001363471, NM_001363472
Synonyms	2810018E08Rik; AI840684
Summary	GTPase, binds and hydrolyzes GTP. Involved in intracellular vitamin B12 metabolism, mediates the transport of cobalamin (Cbl) into mitochondria for the final steps of adenosylcobalamin (AdoCbl) synthesis. Functions as a G-protein chaperone that assists AdoCbl cofactor delivery from MMAB to the methylmalonyl-CoA mutase (MMUT) and reactivation of the enzyme during catalysis.[UniProtKB/Swiss-Prot Function]

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