Mouse Aida activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Aida
Locus ID	108909
Kit Components	GA212161G1, Aida gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212161G2, Aida gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212161G3, Aida gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_145626, NM_181732
Synonyms	2610208M17Rik; BC004835
Summary	Acts as a ventralizing factor during embryogenesis (By similarity). Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.[UniProtKB/Swiss-Prot Function]

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